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Upstream Biotechnology

Durham, United States (US) · Health and Medical

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Upstream Biotechnology is a Durham, North Carolina-based biotechnology company dedicated to engineering crop resilience for a sustainable food future.With the global population projected to reach 10 billion by 2050, Upstream Biotechnology addresses the urgent need for increased agricultural productivity in the face of climate change and evolving food security challenges.Our patented SwitchBlade Technology utilizes natural RNA-based solutions to modulate plant immunity, providing broad-spectrum resistance against diseases and abiotic stresses – all without compromising yield.

Overview

Upstream Biotechnology is a Durham, North Carolina-based biotechnology company dedicated to engineering crop resilience for a sustainable food future.

With the global population projected to reach 10 billion by 2050, Upstream Biotechnology addresses the urgent need for increased agricultural productivity in the face of climate change and evolving food security challenges.

Our patented SwitchBlade Technology utilizes natural RNA-based solutions to modulate plant immunity, providing broad-spectrum resistance against diseases and abiotic stresses – all without compromising yield. We are focused on partnering with seed companies to deliver next-generation traits that enhance grower profitability and build resilience across the value chain.

Upstream Biotechnology is currently developing a pipeline of traits for key crops, including soy, and actively seeking collaborations for field trials and commercialization.
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Contact Details

contact@upstreambiotech.com

Durham, United States (US), 701 West Main Street

Founded

2018

Company Type

Private Limited Company

Employees

2-10

Categories

Biopharma
Life Science
Biotechnology

Awards

• 2026 OpenSee all

Products

Default Product Image
SwitchBlade Technology
Biotechnology

Our patented genetic platform modulates plant immunity for broad spectrum resistance with no yield drag. This RNA-based solution quietly monitors for stress and then flips the plant’s natural defenses on at the right time and in the right tissues, delivering broad protection with no yield drag.

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